Frequency and outcomes of severe hyperlactatemia after elective cardiac surgery

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Frequency, risk factors, and outcome of hyperlactatemia after cardiac surgery.

STUDY OBJECTIVE To determine the respective frequencies, risk factors, and outcomes of no hyperlactatemia (NHL), immediate hyperlactatemia (IHL), or late hyperlactatemia (LHL) > 3 mmol/L after cardiac surgery. DESIGN Prospective and observational study. SETTING Cardiac surgery ICU in a 130-bed private community nonteaching hospital. PATIENTS Consecutive patients (n = 325) undergoing cardi...

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Hyperlactatemia and Cardiac Surgery.

The normal blood lactate level is 0-2 mmol/L, and a value above 3-5 mmol/L is variably used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from both hypoxic and non-hypoxic mechanisms. The major non-hypoxic mechanism is likely stress-induced accelerated aerobic metabolism, in which elevated lactate results from a mass effect on the lactate/pyruvate equilibriu...

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Hyperlactatemia in critical illness and cardiac surgery

suggest a diff ering association between early and late hyperlactatemia and mortality in post-operative cardiac surgery patients and that the inclusion of this cohort in our 'cardiac/vascular' group may have weakened the association between lactate and mortality in our study. Th ey are correct in assuming that a signifi cant number of patients from the 'cardiac/vascular' group were post-operati...

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Preoperative blood glucose concentrations and postoperative outcomes after elective non-cardiac surgery: an observational study.

BACKGROUND The association between preoperative blood glucose (BG) concentration and outcomes after non-cardiac surgery and the impact of the diabetes diagnosis status remain unclear. We tested two hypotheses: that preoperative BG is related to surgical outcomes; and that this relationship depends on the diabetes diagnosis status of the patient. METHODS We retrospectively analysed data on 61 ...

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Early hyperlactatemia predicts pancreatic fistula after surgery

BACKGROUND Postoperative pancreatic fistula (POPF) is a major complication after pancreatic surgery and results from an impaired healing of the pancreatic enteric anastomosis. Whether perioperative hemodynamic fluid management aiming to provide an adequate tissue perfusion could influence the occurrence of POPF is unknown. Serum lactate level is a well-recognized marker of decreased tissue perf...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 2016

ISSN: 0022-5223

DOI: 10.1016/j.jtcvs.2015.10.063